Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase/Protein DBF4 homolog A' and Ligand = 'BDBM50016167'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM50016167 (CHEMBL3261518) Show SMILES CN(C)c1nc(sc1C(N)=O)-c1ccnc(N)n1 Show InChI InChI=1S/C10H12N6OS/c1-16(2)8-6(7(11)17)18-9(15-8)5-3-4-13-10(12)14-5/h3-4H,1-2H3,(H2,11,17)(H2,12,13,14)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assay				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM50016167 (CHEMBL3261518) Show SMILES CN(C)c1nc(sc1C(N)=O)-c1ccnc(N)n1 Show InChI InChI=1S/C10H12N6OS/c1-16(2)8-6(7(11)17)18-9(15-8)5-3-4-13-10(12)14-5/h3-4H,1-2H3,(H2,11,17)(H2,12,13,14)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrs				Eur J Med Chem 80: 364-82 (2014) Article DOI: 10.1016/j.ejmech.2014.04.013 BindingDB Entry DOI: 10.7270/Q2NC62R8
					More data for this Ligand-Target Pair