Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase' and Ligand = 'BDBM185860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM185860 (US9163007, 200) Show SMILES COc1ccc(NC(=O)Nc2n[nH]c3ccc(cc23)-c2nnn(Cc3ccccc3)c2-c2ccccc2)cc1 Show InChI InChI=1S/C30H25N7O2/c1-39-24-15-13-23(14-16-24)31-30(38)32-29-25-18-22(12-17-26(25)33-35-29)27-28(21-10-6-3-7-11-21)37(36-34-27)19-20-8-4-2-5-9-20/h2-18H,19H2,1H3,(H3,31,32,33,35,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
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