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Found 1 hit Enz. Inhib. hit(s) with Target = 'Chloroquine resistance transporter' and Ligand = 'BDBM50353744'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloroquine resistance transporter


(Plasmodium falciparum)		BDBM50353744
PNG
(CHEMBL1830986)
Show SMILES CN(Cc1ccccc1)Cc1cccc(CNc2ccnc3cc(Cl)ccc23)c1
Show InChI InChI=1S/C25H24ClN3/c1-29(17-19-6-3-2-4-7-19)18-21-9-5-8-20(14-21)16-28-24-12-13-27-25-15-22(26)10-11-23(24)25/h2-15H,16-18H2,1H3,(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



University of Cape Town

Curated by ChEMBL


Assay Description
Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi...

J Med Chem 54: 6956-68 (2011)


Article DOI: 10.1021/jm2009698
BindingDB Entry DOI: 10.7270/Q2GB24FN
More data for this
Ligand-Target Pair