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Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2' and Ligand = 'BDBM50269701'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromatin remodeling regulator CECR2


(Homo sapiens (Human))		BDBM50269701
PNG
(CHEMBL4078864)
Show SMILES C[C@@H](N1CCC(CC1)N(C)C(=O)c1cn(CC=C)c(=O)c2[nH]c(C)cc12)c1ccccc1 |r|
Show InChI InChI=1S/C26H32N4O2/c1-5-13-30-17-23(22-16-18(2)27-24(22)26(30)32)25(31)28(4)21-11-14-29(15-12-21)19(3)20-9-7-6-8-10-20/h5-10,16-17,19,21,27H,1,11-15H2,2-4H3/t19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal His6-FLAG-tagged CECR2 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay

ACS Med Chem Lett 8: 737-741 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00132
BindingDB Entry DOI: 10.7270/Q2862JXN
More data for this
Ligand-Target Pair