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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 5' and Ligand = 'BDBM50194467'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 5


(Homo sapiens (Human))
BDBM50194467
PNG
(CHEMBL3918626)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C)C1CNC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1/C41H60N8O9/c1-26(2)20-32(40(56)46-31(38(54)48-34(25-50)41(57)58-5)18-12-13-19-49(4)30-22-42-23-30)47-36(52)27(3)44-39(55)33(21-28-14-8-6-9-15-28)45-35(51)24-43-37(53)29-16-10-7-11-17-29/h6-11,14-17,26-27,30-34,42,50H,12-13,18-25H2,1-5H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t27-,31-,32-,33-,34-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
More data for this
Ligand-Target Pair