Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM144341'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM144341 (US8969348, [4-(Naphthalen-1-ylmethyl)-1-oxophthala...) Show SMILES OC(=O)Cn1nc(Cc2cccc3ccccc23)c2ccccc2c1=O Show InChI InChI=1S/C21H16N2O3/c24-20(25)13-23-21(26)18-11-4-3-10-17(18)19(22-23)12-15-8-5-7-14-6-1-2-9-16(14)15/h1-11H,12-13H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	8.0	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....				US Patent US8969348 (2015) BindingDB Entry DOI: 10.7270/Q2J38R8B
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