Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50085352'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50085352 (CHEMBL62222 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1cccc(Cl)c1Cl Show InChI InChI=1S/C19H18Cl3NO2/c20-12-17(24)16(11-13-5-2-1-3-6-13)23-18(25)10-9-14-7-4-8-15(21)19(14)22/h1-8,16H,9-12H2,(H,23,25)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human serine protease chymase				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
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