Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50085353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50085353 (CHEMBL293590 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES CCc1ccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)cc1 Show InChI InChI=1S/C21H24ClNO2/c1-2-16-8-10-17(11-9-16)12-13-21(25)23-19(20(24)15-22)14-18-6-4-3-5-7-18/h3-11,19H,2,12-15H2,1H3,(H,23,25)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human serine protease chymase				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair