Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50093748'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50093748 ((6R,7R)-7-Methoxy-3-(1-methyl-1H-tetrazol-5-ylsulf...) Show SMILES CO[C@]1(NC(=O)c2ccccc2Oc2ccccc2)[C@H]2OCC(CSc3nnnn3C)=C(N2C1=O)C(=O)OCc1ccc(cc1)C(O)=O |c:33| Show InChI InChI=1S/C32H28N6O9S/c1-37-31(34-35-36-37)48-18-21-17-46-30-32(44-2,33-26(39)23-10-6-7-11-24(23)47-22-8-4-3-5-9-22)29(43)38(30)25(21)28(42)45-16-19-12-14-20(15-13-19)27(40)41/h3-15,30H,16-18H2,1-2H3,(H,33,39)(H,40,41)/t30-,32+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human Serine protease chymase				Bioorg Med Chem Lett 10: 2403-6 (2001) BindingDB Entry DOI: 10.7270/Q23R0S4F
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