Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50208240'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50208240 (1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...) Show SMILES OP(=O)(C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccc(Cl)cc12)c1ccccc1 Show InChI InChI=1S/C26H19ClNO3PS/c27-19-11-13-24-22(15-19)23(16-33-24)25(32(30,31)21-8-2-1-3-9-21)26(29)28-20-12-10-17-6-4-5-7-18(17)14-20/h1-16,25H,(H,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human skin chymase				J Med Chem 50: 1727-30 (2007) Article DOI: 10.1021/jm0700619 BindingDB Entry DOI: 10.7270/Q26W99RF
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