Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50210105'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50210105 ((E)-6-benzylidene-4-(4-chlorophenylsulfonyl)-1,4-d...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N1CC(=O)NC\C(=C/c2ccccc2)C1=O Show InChI InChI=1S/C18H15ClN2O4S/c19-15-6-8-16(9-7-15)26(24,25)21-12-17(22)20-11-14(18(21)23)10-13-4-2-1-3-5-13/h1-10H,11-12H2,(H,20,22)/b14-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3431-4 (2007) Article DOI: 10.1016/j.bmcl.2007.03.038 BindingDB Entry DOI: 10.7270/Q2G160H9
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