Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2 (Homo sapiens (Human)) | BDBM387068 (1-(4-Methoxyphenyl)-7-oxo-6-(2-oxo-[1,4′-bip...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen | Assay Description Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ... | J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2F1921P | |||||||||||
More data for this Ligand-Target Pair |