Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor VII/Tissue factor' and Ligand = 'BDBM50172232'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50172232 (2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-(1-m...) Show SMILES CNc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(NC(C)CCc3ccccc3)c2F)c(c1)C(O)=O Show InChI InChI=1S/C30H29F2N5O4/c1-17(11-12-18-7-4-3-5-8-18)36-26-24(31)28(40-21-10-6-9-19(15-21)27(33)34)37-29(25(26)32)41-23-14-13-20(35-2)16-22(23)30(38)39/h3-10,13-17,35H,11-12H2,1-2H3,(H3,33,34)(H,36,37)(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutes				Bioorg Med Chem Lett 15: 4752-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.059 BindingDB Entry DOI: 10.7270/Q2WD4044
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