Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor VII' and Ligand = 'BDBM14874'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM14874 (1-(3,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...) Show SMILES Oc1c(cccc1-c1cccc(CNC(=O)Nc2ccc(F)c(F)c2)c1)-c1cc2cnccc2[nH]1 Show InChI InChI=1S/C27H20F2N4O2/c28-22-8-7-19(13-23(22)29)32-27(35)31-14-16-3-1-4-17(11-16)20-5-2-6-21(26(20)34)25-12-18-15-30-10-9-24(18)33-25/h1-13,15,33-34H,14H2,(H2,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	330	-36.6	n/a	n/a	n/a	n/a	n/a	7.4	22
Celera					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				Bioorg Med Chem Lett 16: 3197-200 (2006) Article DOI: 10.1016/j.bmcl.2006.03.049 BindingDB Entry DOI: 10.7270/Q20P0X9Q
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