Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor VII' and Ligand = 'BDBM50272578'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM50272578 ((S)-2-[((R)-Pyrrolidine-2-carbonyl)-amino]-pentane...) Show SMILES NC(=O)CC[C@H](NC(=O)[C@H]1CCCN1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C18H26N6O3/c19-15(25)8-7-14(24-18(27)13-2-1-9-22-13)17(26)23-10-11-3-5-12(6-4-11)16(20)21/h3-6,13-14,22H,1-2,7-10H2,(H2,19,25)(H3,20,21)(H,23,26)(H,24,27)/t13-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 7a-tissue factor complex				Bioorg Med Chem Lett 18: 4533-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.044 BindingDB Entry DOI: 10.7270/Q29G5MN3
					More data for this Ligand-Target Pair