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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor VII' and Ligand = 'BDBM50347171'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor VII


(Homo sapiens (Human))		BDBM50347171
PNG
(CHEMBL1797525)
Show SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#6]-c1ccccc1 |r|
Show InChI InChI=1S/C39H46N6O5S/c40-39(41)42-24-14-13-23-33(36(46)27-31-19-9-3-10-20-31)43-37(47)34(25-29-15-5-1-6-16-29)44-38(48)35(26-30-17-7-2-8-18-30)45-51(49,50)28-32-21-11-4-12-22-32/h1-12,15-22,33-35,45H,13-14,23-28H2,(H,43,47)(H,44,48)(H4,40,41,42)/t33-,34-,35+/m0/s1
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Article
PubMed
n/an/a 6.40E+5n/an/an/an/an/an/a



Technical University of Denmark

Curated by ChEMBL


Assay Description
Inhibition of recombinant F7a using S-2288 as substrate after 15 mins by competitive binding assay

Bioorg Med Chem Lett 21: 3918-22 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.025
BindingDB Entry DOI: 10.7270/Q28G8M1V
More data for this
Ligand-Target Pair