Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM130529'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM130529 (US8822458, 126) Show SMILES NC1CCN(C1)c1ccc(cc1F)N1CC(CNC(=O)c2ccc(Cl)s2)OC1=O Show InChI InChI=1S/C19H20ClFN4O3S/c20-17-4-3-16(29-17)18(26)23-8-13-10-25(19(27)28-13)12-1-2-15(14(21)7-12)24-6-5-11(22)9-24/h1-4,7,11,13H,5-6,8-10,22H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	25
Bayer Intellectual Property GmbH US Patent					Assay Description The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...				US Patent US8822458 (2014) BindingDB Entry DOI: 10.7270/Q2VH5MJ2
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