Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM130535'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM130535 (US8822458, 132) Show SMILES Fc1cc(ccc1N1CCC1)N1CC(CNC(=O)c2ccc(Cl)s2)OC1=O Show InChI InChI=1S/C18H17ClFN3O3S/c19-16-5-4-15(27-16)17(24)21-9-12-10-23(18(25)26-12)11-2-3-14(13(20)8-11)22-6-1-7-22/h2-5,8,12H,1,6-7,9-10H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	25
Bayer Intellectual Property GmbH US Patent					Assay Description The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...				US Patent US8822458 (2014) BindingDB Entry DOI: 10.7270/Q2VH5MJ2
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