Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM26361'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM26361 ((2Z)-2-cyano-3-[(3-cyano-1H-indol-7-yl)amino]-N,N-...) Show SMILES CN(C)C(=O)C(C#N)C(N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O)=Nc1cccc2c(c[nH]c12)C#N |r,w:26.28| Show InChI InChI=1S/C27H32N8O3/c1-33(2)26(37)20(15-29)25(31-21-10-7-8-19-18(14-28)16-30-24(19)21)32-22-9-3-4-13-35(27(22)38)17-23(36)34-11-5-6-12-34/h7-8,10,16,20,22,30H,3-6,9,11-13,17H2,1-2H3,(H,31,32)/t20?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.4	22
Bristol-Myers Squibb Company					Assay Description Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...				J Med Chem 51: 7541-51 (2008) Article DOI: 10.1021/jm800855x BindingDB Entry DOI: 10.7270/Q2V12332
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