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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50024529'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50024529
PNG
(CHEMBL3330482)
Show SMILES [H][C@@]12CSc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1ccc(Cl)s1)N1CCOCC1=O |r|
Show InChI InChI=1/C20H18ClN3O5S2/c21-17-4-3-15(31-17)19(26)22-8-14-13-10-30-16-7-11(23-5-6-28-9-18(23)25)1-2-12(16)24(13)20(27)29-14/h1-4,7,13-14H,5-6,8-10H2,(H,22,26)/t13-,14-/s2
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrate


J Med Chem 57: 7770-91 (2014)


Article DOI: 10.1021/jm501045e
BindingDB Entry DOI: 10.7270/Q228095Z
More data for this
Ligand-Target Pair