Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50074115'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50074115 (CHEMBL3409880) Show SMILES COc1ccc(NC(=O)C(=O)Nc2ccc(Cl)cn2)c(c1)C(=O)Nc1ccc(cc1)N1CCOCC1=O Show InChI InChI=1S/C25H22ClN5O6/c1-36-18-7-8-20(29-24(34)25(35)30-21-9-2-15(26)13-27-21)19(12-18)23(33)28-16-3-5-17(6-4-16)31-10-11-37-14-22(31)32/h2-9,12-13H,10-11,14H2,1H3,(H,28,33)(H,29,34)(H,27,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human factor 10a using acromogenic substrate S-2222 preincubated for 30 mins before substrate addition measured after 20 mins by spectr...				Eur J Med Chem 95: 388-99 (2015) Article DOI: 10.1016/j.ejmech.2015.03.052 BindingDB Entry DOI: 10.7270/Q29G5PH4
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