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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50216583'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216583
PNG
(3-chloro-N-((1R,2S)-2-(4-(2-oxopyrazin-1(2H)-yl)be...)
Show SMILES Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(cc1)-n1ccncc1=O
Show InChI InChI=1S/C26H24ClN5O3/c27-20-14-29-23-13-17(7-10-19(20)23)26(35)31-22-4-2-1-3-21(22)30-25(34)16-5-8-18(9-6-16)32-12-11-28-15-24(32)33/h5-15,21-22,29H,1-4H2,(H,30,34)(H,31,35)/t21-,22+/m0/s1
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Article
PubMed
0.940n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair