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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50218308'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218308
PNG
(5-chloro-N-((3R,4S)-1-(methylsulfonyl)-4-(4-(2-oxo...)
Show SMILES CS(=O)(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O
Show InChI InChI=1S/C22H21ClN4O5S2/c1-34(31,32)26-12-16(17(13-26)25-22(30)18-9-10-19(23)33-18)24-21(29)14-5-7-15(8-6-14)27-11-3-2-4-20(27)28/h2-11,16-17H,12-13H2,1H3,(H,24,29)(H,25,30)/t16-,17+/m0/s1
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Article
PubMed
0.440n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair