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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50338680'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50338680
PNG
((E)-2-(5-chlorothiophen-2-yl)-N-((S)-1-(2-fluoro-4...)
Show SMILES Fc1cc(ccc1N1CC[C@H](NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O)[C@H]1CCCN1 |r|
Show InChI InChI=1S/C20H21ClFN3O3S2/c21-19-6-4-14(29-19)8-11-30(27,28)24-17-7-10-25(20(17)26)18-5-3-13(12-15(18)22)16-2-1-9-23-16/h3-6,8,11-12,16-17,23-24H,1-2,7,9-10H2/b11-8+/t16-,17+/m1/s1
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MMDB

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PC cid
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Article
PubMed
3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrate


Bioorg Med Chem Lett 21: 1582-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.131
BindingDB Entry DOI: 10.7270/Q28052WG
More data for this
Ligand-Target Pair