Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM303783'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM303783 (4-{[2-(10-Chloro-2,5-dioxo-2,5,6,7-tetrahydro-3H-p...) Show SMILES CCC(C(=O)Nc1ccc(cc1)C(O)=O)n1cc2c(cc1=O)-c1cc(Cl)ccc1CNC2=O |$;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;HN;;$| Show InChI InChI=1S/C24H20ClN3O5/c1-2-20(23(31)27-16-7-4-13(5-8-16)24(32)33)28-12-19-18(10-21(28)29)17-9-15(25)6-3-14(17)11-26-22(19)30/h3-10,12,20H,2,11H2,1H3,(H,26,30)(H,27,31)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...				US Patent US10138236 (2018) BindingDB Entry DOI: 10.7270/Q2445PH4
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