Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cobra venom factor/Complement factor B/Complement factor D' and Ligand = 'BDBM251380'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cobra venom factor/Complement factor B/Complement factor D (Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)	BDBM251380 (US9452990, 60) Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1C)C(=O)C[C@@H](N)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H28F2N6O3/c1-13-12-31(19(33)11-17(27)14-4-6-15(25)7-5-14)8-9-32(13)24-29-21-16(23(28)30-24)10-18(34-2)22(35-3)20(21)26/h4-7,10,13,17H,8-9,11-12,27H2,1-3H3,(H2,28,29,30)/t13-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	25
NOVARTIS AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9452990 (2016) BindingDB Entry DOI: 10.7270/Q2H130Z9
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