Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cobra venom factor/Complement factor B/Complement factor D' and Ligand = 'BDBM251387'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cobra venom factor/Complement factor B/Complement factor D (Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)	BDBM251387 (US9452990, 67) Show SMILES CCC[C@H]1CN(CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1)C(=O)C[C@@H](N)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C27H32FN7O3/c1-4-5-18-15-34(22(36)13-20(30)17-8-6-16(14-29)7-9-17)10-11-35(18)27-32-24-19(26(31)33-27)12-21(37-2)25(38-3)23(24)28/h6-9,12,18,20H,4-5,10-11,13,15,30H2,1-3H3,(H2,31,32,33)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	25
NOVARTIS AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9452990 (2016) BindingDB Entry DOI: 10.7270/Q2H130Z9
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