Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cobra venom factor/Complement factor B/Complement factor D' and Ligand = 'BDBM251406'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cobra venom factor/Complement factor B/Complement factor D (Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)	BDBM251406 (US9452990, 88) Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NCC(F)(F)F)c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H27F5N6O3/c1-38-18-11-16-21(20(27)22(18)39-2)33-24(34-23(16)31)36-9-7-35(8-10-36)19(37)12-17(32-13-25(28,29)30)14-3-5-15(26)6-4-14/h3-6,11,17,32H,7-10,12-13H2,1-2H3,(H2,31,33,34)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	25
NOVARTIS AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9452990 (2016) BindingDB Entry DOI: 10.7270/Q2H130Z9
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