Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coiled-coil domain-containing protein 6' and Ligand = 'BDBM50203455'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coiled-coil domain-containing protein 6 (Homo sapiens (Human))	BDBM50203455 (CHEMBL3906151) Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(c3)-c3noc(n3)-c3cncc(c3)-c3cnn(C)c3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C31H28ClF3N8O2/c1-41-7-9-43(10-8-41)18-20-3-5-24(13-26(20)31(33,34)35)38-29(44)19-4-6-27(32)25(12-19)28-39-30(45-40-28)22-11-21(14-36-15-22)23-16-37-42(2)17-23/h3-6,11-17H,7-10,18H2,1-2H3,(H,38,44)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Ocean University of China Curated by ChEMBL					Assay Description Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation after 72 hrs by MTT assay				Bioorg Med Chem Lett 26: 5679-5684 (2016) Article DOI: 10.1016/j.bmcl.2016.10.061 BindingDB Entry DOI: 10.7270/Q2J1054S
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