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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coiled-coil domain-containing protein 6' and Ligand = 'BDBM50556136'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coiled-coil domain-containing protein 6


(Homo sapiens (Human))
BDBM50556136
PNG
(CHEMBL4790634)
Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4nc(nc5[nH]ncc45)-c4cccnc4)c3)cc2C(F)(F)F)CC1
UniProtKB/SwissProt

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.40n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human N-terminal GST-HIS6 fused CCDC6-RET fusion protein (Met1 to Ser503 residues) expressed in Sf9 insect cells using TRK-C-derived pe...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112755
BindingDB Entry DOI: 10.7270/Q2J96B20
More data for this
Ligand-Target Pair