Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM181734'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor B (Homo sapiens (Human))	BDBM181734 (US9676728, 6-A (±)-2-(2,2,2-Trifluoro-1-(2-methoxy...) Show SMILES CNC(c1nc2cc(ccc2[nH]1)C#N)(c1ccc(C)cc1OC)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8
					More data for this Ligand-Target Pair