Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM251884'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor B (Homo sapiens (Human))	BDBM251884 (US9475806, 14-I b) (+)) Show SMILES CCc1cc(C)c2[nH]ccc2c1C(O)(c1nc2cc(cnc2[nH]1)C#N)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...				US Patent US9475806 (2016) BindingDB Entry DOI: 10.7270/Q2KS6QG2
					More data for this Ligand-Target Pair