Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM110042'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM110042 (US9695205, 28) Show SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2ccc(NC(=O)N3CCCC(F)(F)C3)cc12 |r| Show InChI InChI=1S/C34H31ClF3N7O4/c35-23-7-2-1-5-20(23)21-6-3-8-24(29(21)36)41-32(48)27-14-18-13-26(18)45(27)28(46)16-44-25-10-9-19(15-22(25)30(42-44)31(39)47)40-33(49)43-12-4-11-34(37,38)17-43/h1-3,5-10,15,18,26-27H,4,11-14,16-17H2,(H2,39,47)(H,40,49)(H,41,48)/t18-,26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	7.5	25
Achillion Pharmaceuticals, Inc. US Patent					Assay Description Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US9695205 (2017) BindingDB Entry DOI: 10.7270/Q2VQ30TH
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