BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM249380'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Complement factor D


(Homo sapiens (Human))		BDBM249380
PNG
(US9464081, 13)
Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#6])=O)c2ccncc12 |r|
Show InChI InChI=1S/C21H24FN5O3/c1-11(2)15(22)8-24-21(30)17-7-13-6-16(13)27(17)19(29)10-26-18-9-23-5-4-14(18)20(25-26)12(3)28/h4-5,9,13,16-17H,6-8,10H2,1-3H3,(H,24,30)/t13-,16-,17+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 37n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...

US Patent US9464081 (2016)


BindingDB Entry DOI: 10.7270/Q2PN94K2
More data for this
Ligand-Target Pair