Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM254452'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM254452 (US9468661, 30) Show SMILES C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)[C@H]1CC1(Cl)Cl |r| Show InChI InChI=1S/C21H23Cl2N5O3/c1-10(13-8-21(13,22)23)25-18(29)17-7-11-6-16(11)28(17)20(31)26-14-9-27(19(24)30)15-5-3-2-4-12(14)15/h2-5,9-11,13,16-17H,6-8H2,1H3,(H2,24,30)(H,25,29)(H,26,31)/t10-,11-,13-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9468661 (2016) BindingDB Entry DOI: 10.7270/Q23N22B5
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