Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM254484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM254484 (US9468661, 62) Show SMILES CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCC2CC(F)(F)C2)c2ccc(OCc3ncccn3)cc12 |r| Show InChI InChI=1S/C27H28F2N6O4/c1-15(36)25-19-9-18(39-14-23-30-5-2-6-31-23)3-4-20(19)34(33-25)13-24(37)35-21-7-17(21)8-22(35)26(38)32-12-16-10-27(28,29)11-16/h2-6,9,16-17,21-22H,7-8,10-14H2,1H3,(H,32,38)/t17-,21-,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9468661 (2016) BindingDB Entry DOI: 10.7270/Q23N22B5
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