Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM254507'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM254507 (US9468661, 85) Show SMILES C[C@@H]1CCC[C@@H]1CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccncc12 |r| Show InChI InChI=1S/C22H28N6O3/c1-12-3-2-4-13(12)9-25-22(31)17-8-14-7-16(14)28(17)19(29)11-27-18-10-24-6-5-15(18)20(26-27)21(23)30/h5-6,10,12-14,16-17H,2-4,7-9,11H2,1H3,(H2,23,30)(H,25,31)/t12-,13-,14-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9468661 (2016) BindingDB Entry DOI: 10.7270/Q23N22B5
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