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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM360797'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Complement factor D


(Homo sapiens (Human))		BDBM360797
PNG
(1-(2-((2S,4R)-2-(6- bromopyridin-2- ylcarbamoyl)-4...)
Show SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)C#Cc1ncc(F)cn1 |r|
Show InChI InChI=1S/C26H19BrF2N8O3/c27-20-2-1-3-22(33-20)34-26(40)19-9-15(28)12-36(19)23(38)13-37-18-6-4-14(8-17(18)24(35-37)25(30)39)5-7-21-31-10-16(29)11-32-21/h1-4,6,8,10-11,15,19H,9,12-13H2,(H2,30,39)(H,33,34,40)/t15-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals, Inc.

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...

US Patent US9828396 (2017)


BindingDB Entry DOI: 10.7270/Q2WM1GQG
More data for this
Ligand-Target Pair