Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131868'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131868 (US8835444, 3.3) Show SMILES Cc1cc(nn1C[C@H]1CC[C@H](CC1)NC(=O)c1cc(Cl)cnc1C)-c1ccc(F)cc1 |r,wU:10.14,7.7,(1.07,-.38,;2.4,.38,;3.87,-.09,;4.77,1.15,;3.87,2.4,;2.4,1.93,;1.07,2.69,;-.26,1.93,;-.26,.38,;-1.6,-.38,;-2.93,.38,;-2.93,1.93,;-1.6,2.69,;-4.26,-.38,;-5.6,.38,;-5.6,1.93,;-6.93,-.38,;-8.27,.38,;-9.6,-.38,;-10.93,.38,;-9.6,-1.93,;-8.27,-2.69,;-6.93,-1.93,;-5.6,-2.69,;6.31,1.15,;7.08,-.18,;8.62,-.18,;9.39,1.15,;10.93,1.15,;8.62,2.49,;7.08,2.49,)| Show InChI InChI=1S/C24H26ClFN4O/c1-15-11-23(18-5-7-20(26)8-6-18)29-30(15)14-17-3-9-21(10-4-17)28-24(31)22-12-19(25)13-27-16(22)2/h5-8,11-13,17,21H,3-4,9-10,14H2,1-2H3,(H,28,31)/t17-,21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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