Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131870 (US8835444, 3.17) Show SMILES Cc1cc(C)n(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(cnc2C)C(F)(F)F)n1 |r,wU:7.6,wD:10.13,(9.29,1.15,;7.75,1.15,;6.84,-.09,;5.38,.38,;4.05,-.38,;5.38,1.93,;4.05,2.69,;2.71,1.93,;2.71,.38,;1.38,-.38,;.05,.38,;.05,1.93,;1.38,2.69,;-1.29,-.38,;-2.62,.38,;-2.62,1.93,;-3.96,-.38,;-5.29,.38,;-6.62,-.38,;-6.62,-1.93,;-5.29,-2.69,;-3.96,-1.93,;-2.62,-2.69,;-7.96,.38,;-9.29,-.38,;-7.96,1.93,;-9.29,1.15,;6.84,2.4,)| Show InChI InChI=1S/C20H25F3N4O/c1-12-8-13(2)27(26-12)11-15-4-6-17(7-5-15)25-19(28)18-9-16(20(21,22)23)10-24-14(18)3/h8-10,15,17H,4-7,11H2,1-3H3,(H,25,28)/t15-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	634	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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