Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131871'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131871 (US8835444, 4.1) Show SMILES COc1ccc(cc1)-c1cc(C)n(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)n1 |r,wU:14.14,wD:17.21,(11.26,-3.73,;9.78,-4.13,;8.69,-3.04,;7.2,-3.44,;6.11,-2.35,;6.51,-.87,;8,-.47,;9.09,-1.56,;5.42,.22,;5.9,1.69,;4.65,2.59,;4.65,4.13,;3.41,1.69,;2.07,2.46,;.74,1.69,;.74,.15,;-.6,-.62,;-1.93,.15,;-1.93,1.69,;-.6,2.46,;-3.26,-.62,;-4.6,.15,;-4.6,1.69,;-5.93,-.62,;-7.26,.15,;-8.6,-.62,;-8.6,-2.16,;-7.26,-2.93,;-5.93,-2.16,;-4.6,-2.93,;-9.93,.15,;-11.26,-.62,;-9.93,1.69,;-11.26,.92,;3.88,.22,)| Show InChI InChI=1S/C26H27ClF3N3O2/c1-16-13-24(18-5-10-21(35-2)11-6-18)32-33(16)15-17-3-8-20(9-4-17)31-25(34)22-14-19(26(28,29)30)7-12-23(22)27/h5-7,10-14,17,20H,3-4,8-9,15H2,1-2H3,(H,31,34)/t17-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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