Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131881'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131881 (US8835444, 5.26) Show SMILES CCc1cc(C)nn1C[C@H]1CC[C@@H](CC1)NC(=O)c1cc(ccc1Cl)C(F)(F)F |r,wU:9.9,wD:12.16,(5.9,-2.27,;5.13,-.94,;5.9,.39,;7.44,.39,;7.91,1.86,;9.25,2.63,;6.67,2.76,;5.42,1.86,;4.09,2.63,;2.76,1.86,;2.76,.32,;1.42,-.45,;.09,.32,;.09,1.86,;1.42,2.63,;-1.25,-.45,;-2.58,.32,;-2.58,1.86,;-3.91,-.45,;-5.25,.32,;-6.58,-.45,;-6.58,-1.99,;-5.25,-2.76,;-3.91,-1.99,;-2.58,-2.76,;-7.91,.32,;-7.91,1.86,;-9.25,-.45,;-9.25,1.09,)| Show InChI InChI=1S/C21H25ClF3N3O/c1-3-17-10-13(2)27-28(17)12-14-4-7-16(8-5-14)26-20(29)18-11-15(21(23,24)25)6-9-19(18)22/h6,9-11,14,16H,3-5,7-8,12H2,1-2H3,(H,26,29)/t14-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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