Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM20937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM20937 (2-Aryloxy-4-alkoxy-pyridine, 18 | methyl 6-methyl-...) Show SMILES CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1C(=O)OC Show InChI InChI=1S/C22H29NO4/c1-8-17(9-2)26-18-12-16(6)23-21(19(18)22(24)25-7)27-20-14(4)10-13(3)11-15(20)5/h10-12,17H,8-9H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	7.0	22
Pfizer					Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro.				J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH
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