Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50074462'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074462 ((1-Ethyl-pentyl)-[5-methyl-3-(2,4,6-trimethyl-phen...) Show SMILES CCCCC(CC)Nc1nc(C)nc2n(nnc12)-c1c(C)cc(C)cc1C |(8.12,-8.03,;8.12,-6.47,;9.45,-5.7,;9.45,-4.16,;10.78,-3.39,;10.78,-1.84,;9.45,-1.07,;12.12,-4.16,;12.12,-5.7,;10.78,-6.47,;10.78,-8.01,;9.43,-8.78,;12.12,-8.78,;13.45,-8.01,;14.91,-8.48,;15.8,-7.23,;14.91,-6,;13.45,-6.47,;15.24,-9.99,;16.69,-10.46,;17.83,-9.43,;17.02,-11.95,;15.89,-13,;16.22,-14.5,;14.42,-12.51,;14.09,-11.02,;12.62,-10.55,)| Show InChI InChI=1S/C21H30N6/c1-7-9-10-17(8-2)24-20-18-21(23-16(6)22-20)27(26-25-18)19-14(4)11-13(3)12-15(19)5/h11-12,17H,7-10H2,1-6H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair