Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50076785'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076785 (2,5,6-Trimethyl-4-(2-trifluoromethyl-phenyl)-7-(2,...) Show SMILES Cc1c(C)c2c(nc(C)nc2n1-c1c(C)cc(C)cc1C)-c1ccccc1C(F)(F)F |(10.94,-6.24,;9.41,-6.24,;8.5,-5,;8.98,-3.54,;7.03,-5.47,;5.71,-4.71,;4.36,-5.47,;4.36,-7.01,;3.03,-7.78,;5.68,-7.8,;7.03,-7.01,;8.5,-7.49,;8.99,-8.96,;7.94,-10.1,;6.44,-9.79,;8.42,-11.57,;9.93,-11.89,;10.41,-13.36,;10.96,-10.73,;10.49,-9.27,;11.51,-8.13,;5.68,-3.16,;7.03,-2.38,;7.03,-.82,;5.68,-.05,;4.36,-.84,;4.36,-2.38,;3.03,-3.15,;1.82,-3.85,;1.54,-2.58,;2.78,-4.73,)| Show InChI InChI=1S/C25H24F3N3/c1-13-11-14(2)23(15(3)12-13)31-17(5)16(4)21-22(29-18(6)30-24(21)31)19-9-7-8-10-20(19)25(26,27)28/h7-12H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
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