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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50116097'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50116097
PNG
(CHEMBL66719 | [5-Methyl-3-(2,4,6-trimethyl-phenyl)...)
Show SMILES CCCN(CCC)c1nc(C)nc2c(n[nH]c12)-c1c(C)cc(C)cc1C |(-1.63,3.13,;-2.98,2.39,;-3.01,.86,;-4.36,.11,;-5.68,.9,;-5.65,2.44,;-6.97,3.23,;-4.39,-1.43,;-5.74,-2.18,;-5.78,-3.72,;-7.13,-4.46,;-4.46,-4.51,;-3.1,-3.76,;-1.65,-4.28,;-.72,-3.04,;-1.6,-1.77,;-3.07,-2.22,;-1.19,-5.75,;-2.24,-6.87,;-3.75,-6.52,;-1.8,-8.34,;-.3,-8.69,;.16,-10.16,;.75,-7.54,;.3,-6.07,;1.34,-4.95,)|
Show InChI InChI=1S/C21H29N5/c1-7-9-26(10-8-2)21-20-19(22-16(6)23-21)18(24-25-20)17-14(4)11-13(3)12-15(17)5/h11-12H,7-10H2,1-6H3,(H,24,25)
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PubMed
 16n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cells

Bioorg Med Chem Lett 12: 2133-6 (2002)


BindingDB Entry DOI: 10.7270/Q2SQ8ZPK
More data for this
Ligand-Target Pair