Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50132894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132894 (CHEMBL334262 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(8.04,5.07,;8.6,3.62,;7.63,2.42,;8.19,1,;9.71,.75,;10.69,1.96,;12.21,1.72,;10.12,3.39,;7.21,-.22,;7.79,-1.64,;6.81,-2.85,;7.37,-4.29,;5.29,-2.62,;4.73,-1.18,;3.28,-.64,;2.04,-1.54,;2.21,-3.07,;.96,-3.98,;-.46,-3.35,;-1.71,-4.26,;-.62,-1.82,;.64,-.91,;.48,.63,;3.35,.88,;2.15,1.84,;4.84,1.3,;5.69,.02,)| Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(18)25-26(3)21(20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
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