BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50132923'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50132923
PNG
(CHEMBL326156 | Cyclopropylmethyl-[3-(2,4-dichloro-...)
Show SMILES CCCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H28Cl2N4/c1-4-5-6-11-29(14-16-7-8-16)20-12-15(2)26-22-21(27-28(3)23(20)22)18-10-9-17(24)13-19(18)25/h9-10,12-13,16H,4-8,11,14H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 1.5n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells

Bioorg Med Chem Lett 13: 3371-4 (2003)


BindingDB Entry DOI: 10.7270/Q21C1W8F
More data for this
Ligand-Target Pair