Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50132927'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132927 (Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...) Show SMILES CCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-4-5-10-28(13-15-6-7-15)19-11-14(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132927 (Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...) Show SMILES CCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-4-5-10-28(13-15-6-7-15)19-11-14(2)25-21-20(26-27(3)22(19)21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair