Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50203593'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50203593 (CHEMBL248367 | [8-(2-chloro-4,6-dimethyl-phenyl)-2...) Show SMILES CN(Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12)Cc1cccnc1 |(19,-35.87,;20,-37.03,;19.48,-38.48,;20.47,-39.66,;20.1,-41.15,;18.67,-41.73,;21.41,-41.97,;22.58,-40.98,;24.12,-40.87,;25.11,-42.05,;26.62,-41.78,;27.14,-40.33,;27.61,-42.95,;27.08,-44.41,;28.07,-45.59,;25.56,-44.68,;24.58,-43.5,;23.06,-43.76,;24.5,-39.38,;25.86,-38.66,;25.92,-37.11,;24.55,-36.22,;23.24,-37.01,;23.19,-38.56,;22,-39.55,;21.51,-36.77,;22.04,-35.33,;23.56,-35.07,;24.09,-33.63,;23.11,-32.44,;21.58,-32.71,;21.06,-34.16,)| Show InChI InChI=1S/C25H25ClN6/c1-16-11-17(2)23(20(26)12-16)32-24-21(8-6-10-28-24)31-22(18(3)29-25(31)32)15-30(4)14-19-7-5-9-27-13-19/h5-13H,14-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP production				Bioorg Med Chem Lett 17: 2026-30 (2007) Article DOI: 10.1016/j.bmcl.2007.01.008 BindingDB Entry DOI: 10.7270/Q21R6Q5Q
					More data for this Ligand-Target Pair